User:JoaoMagalhaes
From FreeBio
João Pedro de Magalhães
The aim of my career is to understand why we age and how to slow, stop, and reverse the human aging process.
Biosketch
Presently, I am a postdoctoral fellow at the Harvard-Lipper Center for Computational Genetics, part of the Church lab, affiliated with the Department of Genetics from Harvard Medical School. I use different approaches and strategies to research human aging: gene networks and systems biology, molecular phylogenetics and evolutionary theory, comparative genomics, population genetics, demographic and cellular studies, clinical genetics, and progeroid syndromes. My mentor is George Church.
As a doctoral fellow I worked at the The University of Namur — Facultés Universitaires Notre-Dame de la Paix in Namur, Belgium. Olivier Toussaint was my supervisor at the Ageing and Stress Group part of the Research Unit on Cellular Biology. My research combined theoretical and experimental biology: from the evolutionary theory of aging, passing through the molecular mechanisms of cellular senescence and stress-induced senescence--such as the telomeres, gene expression, and Werner's syndrome--and ending in bioinformatics and genomics. The resulting thesis was entitled: "Modelling human ageing: role of telomeres in stress-induced premature senescence and design of anti-ageing strategies".
I was an undergraduate at the College of Biotechnology, Porto, Portugal, part of the Catholic University of Portugal, where I became a Licentiate in Microbiology.
For almost nine months I was a research intern at the Institute for Molecular and Cell Biology, part of University of Porto. I worked at the Human Genetics and Genetic Disorders on Machado-Joseph disease, a neurologic disorder. My advisor was Jorge Sequeiros.
