Harvard iGEM 2005 Ideas
From FreeBio
Research groups- Post references here.
Tag! / BioWire (Signal Transfer) Paula, Patrick, Jenny, Kang-Xing
Thermal / Diagnostic Detection Chris, Yves, Thomas, Danny, Connie
Cell Density Detection Yin, Hing, Orr, Sasha
BactoSketch/MagnaDoodle/Etch-a-Sketch Yin
Reporter Systems (for all groups)
Contents |
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BioWire
Pros-
- Different kinds of signals, Don't have insulation.
- Cells that receive, versus ones that don't
- Multiplexing,
- No explicit connections, self organizing lines
- Use of photolithography
Cons-
- Very macroscopic
- Slower than electrical wires.
- Could be done with gap junctions
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Bacto-Sketch
Pros-
- Different sensing areas
- Outputs are useful
- Cool.
- Short input time.
- Genetic Latch
- Like UT.
- Like the coaster idea.
Cons-
- UV pen.
- Will Ecoli produce the substances we want, when they are struggling
- Kind of similar to UT.
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Coaster
Pros-
- Links with other projects
- Sensing different levels
- not long is the response time.
- Neat
Cons-
- length of the stimuli
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QS-(spray)
Pros-
- Wider reaching implictions
- Good background research
- Other testing methods.
- Biologically inert
Cons-
- Has a non-biological.
- Testing with non-preengineered cells.
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Formal Project Ideas
Numbers
- Biowire - 5
- Sketch - 6
- Coaster - 4
- QS - 3
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BioWire
| Kang-Xing | Orr | Danny | Patrick |
| Connie | Sasha | Paula |
Tasks:
- Photolithography
- Modelling
- Signaling molecules (AHL, others) and detection.
- Microscopy/visualization
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Bacto-Sketch/Coaster
| Yin | Thomas | Hing |
| Yves | Chris | Jenny |
Tasks:
- Stable film - UT
- UV pen
- Circuit Design
- Signaling of on/off (UV and Temp sensing)
- Reporter system
Tasks for both:
- Circuit design
- Literature/Part Research
- Find ways of fast (non-transcriptional) reporting.
